Abstract: Introduction: surgical treatment of an area of accumulation of breast microcalcifications requires the surgeon to choose the optimal method of surgery. For a long time, the gold standard of surgery was the placement of a wire needle under X-ray control and subsequent removal. In our study, we want to demonstrate one of new methods, which is based on the placement of ultrasound marks in the area of accumulation of calcifications at the preoperative stage and further removal under the control of ultrasound device. Aim: was to make comparative analysis and estimate the effectiveness of preoperative marking with ultrasound-positive (US-positive) marks in patients with non-palpable breast neoplasms. Material and methods: the study included 165 patients (age 32 - 71 years). Patients were divided into three groups depending on the preoperative marking. The first group: installed ultrasound-positive Gel Mark UltraCor Bard marks in the region of microcalcifications at the outpatient stage. The second group: marking with a wire needle «DuaLok» Bard immediately before the operation. The third group: according to results of a repeated preoperative examination, which included: unilateral mammography in two projections with marker, a skin mark was established in the projection of a non-palpable formation. Results: study showed that when choosing a surgical treatment using ultrasound-positive marks, the risk of detecting tumor cells at edges of the resection decreases, the time of surgery is shortened, and the volume of resection of healthy breast tissue is minimized. Study proved that marking using ultrasound-positive marks has an advantage over other methods of preoperative marking and can be implemented in medical organizations that are not equipped with x-ray equipment for marking non-palpable breast formations immediately before surgery. References 1. Kaprin AD, Starinsky VV, Petrova GV. The status of cancer care for the population of Russia in 2018. MNII P.A. Herzen - branch of the Federal State Budgetary Institution Scientific Research Center for Radiology of the Ministry of Health of Russia, 2019: 236 [In Russ]. 2. World Health Organization. World health statistics 2019. https://www.who.int/gho/publications/world_health_statistics/2019/EN_WHS_2019_Main.pdf?ua=1 3. Kaprin AD, Starinsky VV, Petrova GV. Malignant neoplasms in Russia in 2018 (morbidity and mortality). - M.: MNII them. P.A. Herzen - branch of the Federal State Budgetary Institution Scientific Research Center for Radiology of the Ministry of Health of Russia, 2019; 250 [In Russ]. 4. Manuylova OO, Pavlova TV, Didenko VV, et al. Guidelines for the use of the BI-RADS system for mammography examination. Moscow. 2017; 23 [In Russ]. 5. American College of Radiology, ACR BI-RADS Atlas 5th Edition, 2013. 6. Bonfiglio R, Scimeca M, Urbano N, et al. Breast microcalcifications: biological and diagnostic perspectives. Future Oncol. 2018; 14(30): 3097-3099. 7. Tardioli S, Ballesio L, Gigli S, et al. Wire-guided Localization in Non-palpable Breast Cancer: Results from Monocentric Experience. Anticancer Res. 2016; 36(5): 2423-2427.
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Abstract: The article describes main epidemiological, clinical and morphological diagnostic features of a rare form of breast tumor - hamartoma. Current scientific data accompany results of own seven-year research. Diagnostic features (qualitative elastography) of breast hamartoma are described for the first time ever. Authors draw attention to morphological diversity of the breast hamartoma, which leads to complex radiological semiotics. References 1. Malignant diseases in Russia in 2011 (morbidity and mortality). Edited by V.I. Chissov. V.V. Starinsky, G.V. Petrova. M.: FSBI «P.A. Herzen MSROI of the Ministry of Health and Social Development of the Russia», 2013; 289. 2. Tavassoli F.A., Devilee P. (Eds.): World Health Organization classification of Tumours. pathology and genetics of tumours of the breast and female genital organs. IARC Press: Lyon. 2003; 103. 3. Prym P. Pseudoadenome, Adenome and Mastome der weinblichen Brustdruse uber die Entstehung umschriebener adenomahnlicher Herde in die Mamma und uber die Nachahmung des Brustdrusengewebes durch echte Adenome und Fibroadenome. Beitr. Pathol. Anat. Pathol. 1928; 81: 221. 4. Arrigoni M.G., Dockerty M.B., Judd E.S. The identification and treatment of mammary hamartoma. Surg. Gynecol. Obstet. 1971; 133: 577-582. 5. Ruiz-Tovar J., Reguero-Callejas M.E., Arano-Bermejo J.I. et al. Mammary hamartoma. Cir. Esp. 2006; 79 (3): 186-188. 6. Lee W.F., Sheen-Chen S.M., Chi S.Y. et al. Hamartoma of the breast: an underrecognized disease? Tumori. 2008; 94 (1): 114-115. 7. Farrokh D., Hashemi J., Ansaripour E. Breast hamartoma: Mammographic findings. Iran J. Radiol. 2011; 8 (4): 285-260. 8. Mizuta N., Sakaguchi K., Mizuta M. et al. Myoid hamartoma of the breast that proved difficult to diagnose: a case report. World J. Surg. Oncol. 2012; 10 (12): URL: http:www.wjso.com/content/10/1/12. 9. Ravakhah K., Javadi N., Simms R. Hamartoma of the breast in a man: first case report. Breast J. 2001; 7 (4): 266-268. 10. Harigopal M., Mudrovich S.A., Hoda S.A., Rosen P.P. Secondary tumors in mammary adenolipomas: a report of 2 unusual cases. Arch. Pathol. Lab. Med. 2003; 127 (3): e151-e154. 11. Murugesan J.R., Joglekar S., Valerio D. et al. Myoid hamartoma of the breast: case report and review of the literature. Clin. Breast Cancer. 2006; 7: 345-346. 12. Ko M.-S., Jung W.S., Cha E.S., Choi H.J. A rare case of recurrent myoid hamartoma mimicking malignancy: imaging appearances. Korean J. Radiol. 2010; 11 (6): 683-686. 13. Kajo K., Zubor P., Danko J. Myoid (muscular) hamartoma of the breast: case report and review of the literature. Breast care. 2010; 5: 331-334. 14. Ayva S.K., Ozturk F.K., Obut H. Adenohibernoma: a rare breast tumor. Int. J. Surg. Pathol. 2012; 20 (3): 280-283. 15. Nasit J.G., Parikh B., Trivedi P., Shah M. Myoid (muscular) hamartoma of the breast with chondroid metaplasia. Indian J. Pathol. Microbiol. 2012; 55: 121-122.
